:root {
    --hormone-bg: #0b1016;
    --hormone-panel: #151f25;
    --hormone-soft: #202b32;
    --hormone-input: #233139;
    --hormone-border: #34464f;
    --hormone-text: #eef6f4;
    --hormone-muted: #a9b8b5;
    --hormone-amber: #f59e0b;
    --hormone-cyan: #38bdf8;
    --hormone-red: #f87171;
    --hormone-violet: #a78bfa;
}

[data-theme="light"] {
    --hormone-bg: #f5f7f8;
    --hormone-panel: #ffffff;
    --hormone-soft: #edf4f6;
    --hormone-input: #f6fafb;
    --hormone-border: #d3e1e5;
    --hormone-text: #1f2937;
    --hormone-muted: #607078;
}

body {
    background: var(--hormone-bg);
}

body.splash-active {
    overflow: hidden;
}

.container {
    max-width: 1680px;
}

.disclaimer-splash {
    position: fixed;
    inset: 0;
    z-index: 1000;
    display: grid;
    place-items: center;
    padding: 20px;
    background: rgba(5, 10, 14, 0.92);
    backdrop-filter: blur(6px);
}

.disclaimer-splash[hidden] {
    display: none;
}

.disclaimer-splash-panel {
    width: min(920px, 100%);
    max-height: min(86vh, 820px);
    overflow-y: auto;
    padding: 24px;
    border: 1px solid rgba(248, 113, 113, 0.58);
    border-radius: 8px;
    background: var(--hormone-panel);
    color: var(--hormone-text);
    box-shadow: 0 24px 80px rgba(0, 0, 0, 0.45);
}

.disclaimer-splash-panel h2 {
    margin: 16px 0 12px;
    font-size: clamp(1.55rem, 4vw, 2.45rem);
}

.disclaimer-splash-copy {
    display: grid;
    gap: 12px;
    color: var(--hormone-muted);
    line-height: 1.55;
}

.disclaimer-splash-copy p {
    margin: 0;
}

.acknowledgement-line {
    display: grid;
    grid-template-columns: 18px minmax(0, 1fr);
    gap: 10px;
    align-items: start;
    margin-top: 18px;
    padding: 12px;
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    background: var(--hormone-soft);
    color: var(--hormone-text);
    line-height: 1.4;
    font-weight: 700;
}

.acknowledgement-line input {
    margin-top: 3px;
}

.disclaimer-continue {
    width: 100%;
    margin-top: 14px;
}

.disclaimer-continue:disabled {
    cursor: not-allowed;
    opacity: 0.52;
}

header {
    border-bottom: 1px solid var(--hormone-border);
}

.tool-header {
    align-items: center;
}

.tool-header h1 {
    margin: 0;
}

.tagline {
    margin: 6px 0 0;
    color: var(--hormone-muted);
    font-family: "JetBrains Mono", monospace;
    font-size: 0.86rem;
}

.tool-icon-header.biochemical {
    color: var(--hormone-cyan);
}

.hormone-layout {
    display: grid;
    grid-template-columns: minmax(320px, 410px) minmax(0, 1fr) minmax(280px, 360px);
    gap: 20px;
    align-items: start;
}

.liability-banner {
    grid-column: 1 / -1;
    display: flex;
    justify-content: space-between;
    gap: 18px;
    align-items: center;
    padding: 14px 16px;
    border: 1px solid rgba(248, 113, 113, 0.5);
    border-radius: 8px;
    background: rgba(248, 113, 113, 0.12);
    color: var(--hormone-text);
}

.liability-banner p {
    margin: 4px 0 0;
    color: var(--hormone-muted);
    line-height: 1.45;
}

.status-pill {
    display: inline-flex;
    align-items: center;
    justify-content: center;
    white-space: nowrap;
    border-radius: 999px;
    padding: 6px 10px;
    font-family: "JetBrains Mono", monospace;
    font-size: 0.75rem;
    font-weight: 800;
    border: 1px solid var(--hormone-border);
}

.status-pill.locked {
    color: #fecaca;
    background: rgba(127, 29, 29, 0.35);
    border-color: rgba(248, 113, 113, 0.45);
}

.status-pill.active {
    color: #bbf7d0;
    background: rgba(22, 101, 52, 0.32);
    border-color: rgba(34, 197, 94, 0.48);
}

.panel {
    background: var(--hormone-panel);
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
}

.control-panel,
.results-panel,
.side-card {
    padding: 18px;
}

.panel-header {
    display: flex;
    justify-content: space-between;
    align-items: flex-start;
    gap: 14px;
    margin-bottom: 16px;
}

.panel-header h2,
.side-card h2,
.chart-header h3 {
    margin: 0 0 6px;
}

.panel-header p,
.chart-header p,
.side-note {
    margin: 0;
    color: var(--hormone-muted);
    line-height: 1.45;
}

.tool-btn,
.tab-btn {
    border: 1px solid var(--hormone-border);
    background: var(--hormone-soft);
    color: var(--hormone-text);
    border-radius: 8px;
    padding: 9px 12px;
    font: inherit;
    font-weight: 700;
    cursor: pointer;
}

.tool-btn:hover,
.tab-btn:hover {
    border-color: rgba(56, 189, 248, 0.65);
}

.status-line {
    padding: 10px 12px;
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    background: var(--hormone-soft);
    color: var(--hormone-muted);
    font-size: 0.92rem;
}

.status-line.success {
    color: #bbf7d0;
    background: rgba(22, 101, 52, 0.26);
    border-color: rgba(34, 197, 94, 0.45);
}

.scope-warning-block {
    margin-top: 14px;
    padding: 12px;
    border: 1px solid rgba(248, 113, 113, 0.45);
    border-radius: 8px;
    background: rgba(248, 113, 113, 0.10);
}

.scope-warning-block summary {
    cursor: pointer;
    font-weight: 800;
    margin-bottom: 5px;
    color: var(--hormone-red);
}

.scope-warning-block:not([open]) summary {
    margin-bottom: 0;
}

.scope-warning-block strong {
    color: var(--hormone-red);
}

.scope-warning-block p {
    margin: 0 0 8px;
    color: var(--hormone-muted);
    line-height: 1.45;
    font-size: 0.9rem;
}

.scope-warning-block p:last-child {
    margin-bottom: 0;
}

.filter-grid {
    display: grid;
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 12px;
    margin-top: 16px;
}

.filter-preview-note {
    grid-column: 1 / -1;
    margin: 0;
    padding: 8px 10px;
    border: 1px dashed rgba(245, 158, 11, 0.45);
    border-radius: 6px;
    background: rgba(245, 158, 11, 0.08);
    color: var(--hormone-muted);
    font-size: 0.82rem;
    line-height: 1.4;
}

.filter-line {
    display: grid;
    gap: 7px;
    color: var(--hormone-muted);
    font-size: 0.88rem;
    font-weight: 700;
}

.filter-line.wide {
    grid-column: 1 / -1;
}

.filter-line select {
    width: 100%;
    box-sizing: border-box;
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    background: var(--hormone-input);
    color: var(--hormone-text);
    padding: 9px 10px;
    font: inherit;
}

.inline-pair {
    display: grid;
    grid-template-columns: minmax(0, 1fr) minmax(92px, 0.7fr);
    gap: 8px;
}

.result-grid {
    display: grid;
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 12px;
}

.result-card {
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    padding: 14px;
    background: var(--hormone-soft);
}

.locked-card {
    border-color: rgba(245, 158, 11, 0.45);
}

.active-card {
    border-color: rgba(34, 197, 94, 0.42);
}

.result-label {
    color: var(--hormone-muted);
    font-size: 0.78rem;
    font-weight: 800;
    text-transform: uppercase;
}

.result-value {
    margin-top: 6px;
    color: var(--hormone-amber);
    font-family: "JetBrains Mono", monospace;
    font-size: 1.25rem;
    font-weight: 800;
}

[data-theme="light"] .result-value {
    color: #b45309;
}

[data-theme="light"] .empty-state strong,
[data-theme="light"] .gate-list li::before {
    color: #b45309;
}

[data-theme="light"] .gate-list li::before {
    background: #b45309;
    box-shadow: 0 0 0 3px rgba(180, 83, 9, 0.16);
}

.result-card p {
    margin: 8px 0 0;
    color: var(--hormone-muted);
    line-height: 1.45;
    font-size: 0.88rem;
}

.workflow-tabs {
    display: grid;
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 8px;
    margin: 18px 0;
}

.tab-btn.active {
    background: rgba(56, 189, 248, 0.16);
    border-color: var(--hormone-cyan);
}

.view-panel {
    border-top: 1px solid rgba(255, 255, 255, 0.08);
    padding-top: 16px;
}

[data-theme="light"] .view-panel {
    border-top-color: rgba(31, 41, 55, 0.08);
}

.table-scroll {
    overflow-x: auto;
    margin-top: 12px;
}

.reference-table,
.audit-table {
    width: 100%;
    border-collapse: collapse;
    min-width: 760px;
    font-size: 0.88rem;
}

.reference-table th,
.reference-table td,
.audit-table th,
.audit-table td {
    padding: 10px;
    border-bottom: 1px solid var(--hormone-border);
    text-align: left;
    vertical-align: top;
}

.reference-table th,
.audit-table th {
    color: var(--hormone-text);
    font-size: 0.78rem;
    text-transform: uppercase;
}

.reference-table td,
.audit-table td {
    color: var(--hormone-muted);
}

.reference-table .range-value {
    white-space: pre-line;
    color: var(--hormone-text);
    font-family: "JetBrains Mono", monospace;
    font-size: 0.8rem;
}

.reference-table .source-cell {
    min-width: 220px;
}

.source-chip {
    display: inline-flex;
    max-width: 100%;
    padding: 3px 7px;
    border: 1px solid var(--hormone-border);
    border-radius: 999px;
    color: var(--hormone-cyan);
    background: rgba(56, 189, 248, 0.08);
    font-family: "JetBrains Mono", monospace;
    font-size: 0.72rem;
    overflow-wrap: anywhere;
}

a.source-chip {
    text-decoration: none;
}

a.source-chip:hover,
a.source-chip:focus-visible {
    border-color: var(--hormone-cyan);
    background: rgba(56, 189, 248, 0.16);
    outline: none;
}

.source-locator-inline {
    margin-top: 6px;
    font-size: 0.78rem;
    line-height: 1.35;
    overflow-wrap: anywhere;
}

.source-url-inline {
    display: block;
    margin-top: 6px;
    color: var(--hormone-cyan);
    font-family: "JetBrains Mono", monospace;
    font-size: 0.72rem;
    line-height: 1.35;
    overflow-wrap: anywhere;
}

.context-cell,
.method-cell,
.caveat-cell {
    line-height: 1.35;
}

.confidence-cell {
    font-family: "JetBrains Mono", monospace;
    font-size: 0.78rem;
}

.empty-table-message {
    color: var(--hormone-muted);
    text-align: center;
    padding: 18px !important;
}

.chart-shell {
    margin-top: 12px;
    min-height: 340px;
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    background: linear-gradient(180deg, rgba(56, 189, 248, 0.06), rgba(167, 139, 250, 0.05));
    overflow: hidden;
}

.chart-shell svg {
    width: 100%;
    height: 340px;
    display: block;
}

.chart-grid {
    stroke: rgba(169, 184, 181, 0.25);
    stroke-width: 1;
}

.chart-axis {
    stroke: rgba(169, 184, 181, 0.68);
    stroke-width: 1.4;
}

.chart-empty-band {
    fill: rgba(245, 158, 11, 0.10);
    stroke: rgba(245, 158, 11, 0.45);
    stroke-dasharray: 6 5;
}

.cycle-line {
    fill: none;
    stroke: var(--hormone-cyan);
    stroke-width: 2.5;
}

.cycle-band {
    stroke: rgba(167, 139, 250, 0.85);
    stroke-width: 8;
    stroke-linecap: round;
}

.cycle-point {
    fill: var(--hormone-cyan);
    stroke: var(--hormone-bg);
    stroke-width: 2;
}

.chart-label {
    fill: var(--hormone-muted);
    font-family: "JetBrains Mono", monospace;
    font-size: 12px;
}

.chart-title {
    fill: var(--hormone-text);
    font-family: "Space Grotesk", sans-serif;
    font-size: 16px;
    font-weight: 700;
}

.empty-state {
    margin-top: 12px;
    display: grid;
    gap: 6px;
    padding: 16px;
    border: 1px dashed rgba(245, 158, 11, 0.5);
    border-radius: 8px;
    color: var(--hormone-muted);
    background: rgba(245, 158, 11, 0.08);
}

.empty-state strong {
    color: var(--hormone-amber);
}

.cycle-profile-summary {
    margin-top: 14px;
}

.side-card-header {
    display: flex;
    justify-content: space-between;
    align-items: center;
    gap: 10px;
    margin-bottom: 4px;
}

.side-card-header h2 {
    margin: 0;
}

.tool-btn.secondary {
    background: transparent;
}

.analyte-warning-block {
    margin-top: 12px;
    padding: 14px;
    border: 1px solid rgba(245, 158, 11, 0.55);
    border-radius: 8px;
    background: rgba(245, 158, 11, 0.08);
    color: var(--hormone-text);
    display: grid;
    gap: 8px;
}

.analyte-warning-block[hidden] {
    display: none;
}

.analyte-warning-block h3 {
    margin: 0;
    color: var(--hormone-amber);
    font-size: 1rem;
}

.analyte-warning-block .warning-intro {
    margin: 0;
    color: var(--hormone-muted);
    font-size: 0.9rem;
    line-height: 1.45;
}

.analyte-warning-block ul {
    margin: 0;
    padding-left: 18px;
    color: var(--hormone-muted);
    line-height: 1.5;
    font-size: 0.9rem;
    display: grid;
    gap: 6px;
}

.analyte-warning-block .warning-source {
    color: var(--hormone-cyan);
    font-family: "JetBrains Mono", monospace;
    font-size: 0.8rem;
}

.sources-modal-overlay {
    position: fixed;
    inset: 0;
    z-index: 900;
    display: flex;
    align-items: center;
    justify-content: center;
    padding: 24px;
    background: rgba(5, 10, 14, 0.82);
    backdrop-filter: blur(4px);
}

.sources-modal-overlay[hidden] {
    display: none;
}

.sources-modal {
    width: min(900px, 100%);
    max-height: min(86vh, 880px);
    overflow: hidden;
    display: flex;
    flex-direction: column;
    background: var(--hormone-panel);
    border: 1px solid var(--hormone-border);
    border-radius: 10px;
    color: var(--hormone-text);
    box-shadow: 0 24px 60px rgba(0, 0, 0, 0.5);
}

.sources-modal-header {
    display: flex;
    align-items: flex-start;
    justify-content: space-between;
    gap: 16px;
    padding: 18px 20px;
    border-bottom: 1px solid var(--hormone-border);
}

.sources-modal-header h2 {
    margin: 0 0 4px;
}

.modal-close {
    background: transparent;
    color: var(--hormone-text);
    border: 1px solid var(--hormone-border);
    border-radius: 6px;
    width: 32px;
    height: 32px;
    font-size: 1.4rem;
    cursor: pointer;
    line-height: 1;
}

.sources-modal-body {
    padding: 16px 20px 20px;
    overflow-y: auto;
    display: grid;
    gap: 14px;
}

.sources-loading {
    color: var(--hormone-muted);
    margin: 0;
}

.source-entry {
    padding: 12px;
    border: 1px solid var(--hormone-border);
    border-radius: 8px;
    background: var(--hormone-soft);
    display: grid;
    gap: 6px;
}

.source-entry .source-role-pill {
    justify-self: start;
    font-family: "JetBrains Mono", monospace;
    font-size: 0.7rem;
    text-transform: uppercase;
    padding: 3px 8px;
    border-radius: 999px;
    border: 1px solid var(--hormone-border);
    color: var(--hormone-muted);
}

.source-entry .source-locator {
    color: var(--hormone-muted);
    font-size: 0.86rem;
    line-height: 1.4;
}

.source-entry .source-use {
    color: var(--hormone-text);
    font-size: 0.9rem;
    line-height: 1.45;
}

.source-entry a {
    color: var(--hormone-cyan);
    word-break: break-all;
    font-family: "JetBrains Mono", monospace;
    font-size: 0.82rem;
}

.sources-error {
    padding: 12px;
    border: 1px solid rgba(248, 113, 113, 0.55);
    border-radius: 8px;
    background: rgba(248, 113, 113, 0.10);
    color: var(--hormone-red);
}

.side-stack {
    display: grid;
    gap: 20px;
}

.side-card h2 {
    font-size: 1.1rem;
}

.gate-list {
    list-style: none;
    padding: 0;
    margin: 12px 0 0;
    display: grid;
    gap: 10px;
}

.gate-list li {
    display: grid;
    grid-template-columns: 14px minmax(0, 1fr);
    gap: 8px;
    color: var(--hormone-muted);
    line-height: 1.35;
    font-size: 0.9rem;
}

.gate-list li::before {
    content: "";
    width: 10px;
    height: 10px;
    border-radius: 999px;
    margin-top: 5px;
    background: var(--hormone-amber);
    box-shadow: 0 0 0 3px rgba(245, 158, 11, 0.14);
}

@media (max-width: 1180px) {
    .hormone-layout {
        grid-template-columns: minmax(300px, 420px) minmax(0, 1fr);
    }

    .side-stack {
        grid-column: 1 / -1;
        grid-template-columns: repeat(2, minmax(0, 1fr));
    }
}

@media (max-width: 820px) {
    .hormone-layout,
    .side-stack,
    .result-grid,
    .filter-grid,
    .workflow-tabs {
        grid-template-columns: 1fr;
    }

    .liability-banner {
        align-items: flex-start;
        flex-direction: column;
    }

    .inline-pair {
        grid-template-columns: 1fr;
    }

    .disclaimer-splash {
        padding: 12px;
    }

    .disclaimer-splash-panel {
        max-height: 92vh;
        padding: 18px;
    }
}